Actin-alpha/ gamma Polyclonal Antibody

Ab type

Primary antibody

Background

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms| alpha| beta| and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Actin. AA range:21-70

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

41737;41793

synonyms

Actin alpha cardiac muscle 1; ACTC1; ACTC; Actin; alpha cardiac muscle 1; Alpha-cardiac actin; ACTG1; ACTB; ACTG; Actin; cytoplasmic 2; Gamma-actin; ACTG2; ACTA3; ACTL3; ACTSG; Actin; gamma-enteric smooth muscle; Alpha-actin-3; Gamma-2-actin; Smooth muscle gamma-actin;