ACSL5 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity| subcellular localization| and tissue distribution| all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters| and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen| and in trace amounts in normal brain| but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 460-540

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Long-chain-fatty-acid--CoA ligase 5 ;EC 6.2.1.3;Long-chain acyl-CoA synthetase 5;LACS 5