Ace Antibody

Size

100ul

Clone Number

Aliases

Ace antibody; Dcp1 antibody; Angiotensin-converting enzyme antibody; ACE antibody; EC 3.2.1.- antibody; EC 3.4.15.1 antibody; Dipeptidyl carboxypeptidase I antibody; Kininase II antibody; CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme antibody; soluble form] antibody

Immunogen Species

Rattus norvegicus (Rat)

UniProt ID

P47820

Immunogen

Recombinant Rat Angiotensin-converting enzyme protein (1046-1263AA)

Raised in

Rabbit

Species Reactivity

Rat

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

Ace

Research Areas

Cancer; Cardiovascular; Cell biology; Metabolism; Signal transduction; Stem cells