ABCG2 Antibody

Size

100ug

Clone Number

Aliases

ABC transporter antibody; ABC15 antibody; ABCG 2 antibody; ABCG2 antibody; ABCG2_HUMAN antibody; ABCP antibody; ATP binding cassette sub family G (WHITE) member 2 antibody; ATP binding cassette transporter G2 antibody; ATP-binding cassette sub-family G member 2 antibody; BCRP antibody; BCRP1 antibody; BMDP antibody; Breast cancer resistance protein antibody; CD338 antibody; CDw338 antibody; CDw338 antigen antibody; EST157481 antibody; GOUT1 antibody; MGC102821 antibody; Mitoxantrone resistance associated protein antibody; Mitoxantrone resistance-associated protein antibody; MRX antibody; Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2 antibody; MXR antibody; MXR1 antibody; Placenta specific ATP binding cassette transporter antibody; Placenta specific MDR protein antibody; Placenta-specific ATP-binding cassette transporter antibody; UAQTL1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UNQ0

Immunogen

Recombinant Human ATP-binding cassette sub-family G member 2 protein (296-371AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ABCG2

Research Areas

Cancer; Tags & Cell Markers; Metabolism; Signal transduction; Stem cells