ABCC11 Antibody

Size

100ul

Clone Number

Aliases

ABCC 11 antibody; ABCC11 antibody; ABCCB_HUMAN antibody; ATP binding cassette protein C11 antibody; ATP binding cassette sub family C (CFTR/MRP) member 11 antibody; ATP binding cassette sub family C member 11 antibody; ATP binding cassette transporter MRP8 antibody; ATP binding cassette transporter sub family C member 11 antibody; ATP-binding cassette sub-family C member 11 antibody; EWWD antibody; MRP8 antibody; Multi resistance protein 8 antibody; Multidrug resistance associated protein 8 antibody; Multidrug resistance-associated protein 8 antibody; OTTHUMP00000164191 antibody; WW antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96J66

Immunogen

Recombinant Human ATP-binding cassette sub-family C member 11 protein (1-170AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. Probably functions to secrete earwax.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ABCC11

Research Areas

Cancer; Metabolism; Signal transduction