3BP2 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain| an SH3-binding proline-rich region| and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases | and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T| natural killer (NK)| and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 210-290

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

SH3 domain-binding protein 2 ;3BP-2