{"product_id":"yp-ab-18085-10ul","title":"CD3(ABT295)mouse mAb","description":"\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eReaction species:\u003c\/b\u003e Human\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eGene Name:\u003c\/b\u003e CD3E T3E\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eProtein name:\u003c\/b\u003e CD3, CD3E\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eMolecular weight (DA):\u003c\/b\u003e 23kD\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eImmunogen:\u003c\/b\u003e Synthesized peptide derived from human CD3, CD3E AA range: 1-100\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecificity:\u003c\/b\u003e The antibody can specifically recognize human CD3e protein, and shows no reaction with CD3d or CD3g. In western blotting of Jurkat cell lysate, the antibody can label a 23 kDa band corresponding to CD\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eComposition:\u003c\/b\u003e PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Mouse, Monoclonal\/IgG2a, kappa\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eDilution ratio:\u003c\/b\u003e IHC 1:200-1000. WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurification process:\u003c\/b\u003e Protein G\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eConcentration:\u003c\/b\u003e mg\/ml\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage:\u003c\/b\u003e -15°C to -25°C\/1 year(Do not lower than -25°C)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eOther Names:\u003c\/b\u003e 4930549J05Rik；A430104F18Rik；AW552088；Cd247；CD247 antigen；CD247 antigen, zeta subunit；CD247 molecule；CD3；CD3 antigen, delta subunit；CD3 delta；CD3 epsilon；CD3 eta；CD3 gamma；CD3 molecule delta polypeptide；CD3 molecule, epsilon polypeptide；CD3 molecule, gamma polypeptide；CD3 zeta；CD3-DELTA；CD3d；CD3D antigen delta polypeptide；CD3d antigen, delta polypeptide (TiT3 complex)；CD3d molecule delta；CD3d molecule delta CD3 TCR complex；CD3d molecule, delta (CD3-TCR complex)；CD3D_HUMAN；CD3E；CD3e antigen；CD3E antigen epsilon polypeptide；CD3e antigen, epsilon polypeptide (TiT3 complex)；CD3e molecule epsilon；CD3e molecule epsilon CD3 TCR complex；CD3e molecule, epsilon (CD3-TCR complex)；CD3epsilon；CD3G；CD3g antigen；CD3G antigen gamma polypeptide；CD3g antigen, gamma polypeptide (TiT3 complex)；CD3g molecule gamma；CD3g molecule gamma CD3 TCR complex；CD3g molecule, gamma (CD3-TCR complex)；CD3H；CD3Q；CD3Z；CD3zeta；Ctg3；FLJ17620；FLJ17664；FLJ18683；FLJ79544；FLJ94613；IMD19；Leu-4；MGC138597；OKT3, delta chain；OTTHUMP0\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eBackground:\u003c\/b\u003e CD3 protein contains ε、γ、δ and ζ four subunits, including extracellular, transmembrane and intracellular domains. CD3 is a T cell marker, which is not expressed by B cells. CD3 complex mediates TCR antigen recognition, leading to T cell proliferation and cytokine release. It is mainly used for the diagnosis of T-cell lymphoma, with high specificity but low sensitivity. In order to improve the accuracy of diagnosis, it is usually combined with CD45RO in clinical application.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eFunction:\u003c\/b\u003e function:The CD3 complex mediates signal transduction.,online information:CD3E mutation db,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 1 ITAM domain.,subunit:The TCR\/CD3 complex of T-lymphocytes consists of either a TCR alpha\/beta or TCR gamma\/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.,\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Upingbio","offers":[{"title":"10UL","offer_id":50688758087960,"sku":"YP-Ab-18085-10UL","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/images_5755e1cf-e1b2-4d5e-ac8f-c40ee3f78b21.png?v=1758553526","url":"https:\/\/danabiosci.com\/products\/yp-ab-18085-10ul","provider":"Dana Bioscience","version":"1.0","type":"link"}