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Upingbio
SKU:YP-Ab-17078-100UL
K-cadherin Polyclonal Antibody
K-cadherin Polyclonal Antibody
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- Gene Name: CDH6
- Immunogen: Synthesized peptide derived from K-cadherin . at AA range: 180-260
- Specificity: K-cadherin Polyclonal Antibody detects endogenous levels of K-cadherin protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: CDH6; Cadherin-6; Kidney cadherin; K-cadherin
- Background: This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011],
- Function: function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.,
- Species: Human;Mouse;Rat
- Range: WB;IHC;IF;ELISA
- Protein: Cadherin-6
- DA: 88kD
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