{"product_id":"yp-ab-12427-100ul","title":"IL1RA rabbit pAb","description":"\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eGene Name:\u003c\/b\u003e IL1RN IL1F3 IL1RA\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eImmunogen:\u003c\/b\u003e Synthesized peptide derived from human IL1RA\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecificity:\u003c\/b\u003e This antibody detects endogenous levels of Human IL1RA\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eComposition:\u003c\/b\u003e Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Polyclonal, Rabbit,IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eDilution ratio:\u003c\/b\u003e WB 1:1000-2000 ELISA 1:5000-20000\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurification process:\u003c\/b\u003e The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eConcentration:\u003c\/b\u003e 1 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage:\u003c\/b\u003e -20°C\/1 year\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eOther Names:\u003c\/b\u003e Interleukin-1 receptor antagonist protein (IL-1RN;IL-1ra;IRAP;ICIL-1RA;IL1 inhibitor;Anakinra)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eBackground:\u003c\/b\u003e disease:Genetic variation in IL1RN is associated with susceptibility to diabetic nephropathy [MIM:612628]; also called susceptibility to microvascular complications of diabetes type 4 (MVCD4). Diabetic nephropathy is a kidney disease and resultant kidney function impairment due to the long standing effects of diabetes on the microvasculature (glomerulus) of the kidney. Features include increased urine protein and declining kidney function.,function:Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity.,online information:Interleukin-1 entry,online information:The Singapore human mutation and polymorphism database,pharmaceutical:Available under the name Kineret (Amgen). Used for the reduction in signs and symptoms and slowing the progression of structural damage in moderately to severely active rheumatoid arthritis.,similarity:Belongs to the IL-1 family.,tissue specificity:The intracellular form of IL1RN is predominantly expressed in epithelial cells.,\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eFunction:\u003c\/b\u003e defense response, inflammatory response, immune response, response to wounding, response to endogenous stimulus, response to hormone stimulus, response to organic substance, response to corticosteroid stimulus,response to steroid hormone stimulus, response to glucocorticoid stimulus,\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human;Rat;Mouse;\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eRange:\u003c\/b\u003e WB; ELISA\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eProtein:\u003c\/b\u003e IL1RA\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Upingbio","offers":[{"title":"100UL","offer_id":50690887450904,"sku":"YP-Ab-12427-100UL","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/images_662fc783-8996-4d30-b5dc-69247497d0c3.png?v=1758614806","url":"https:\/\/danabiosci.com\/products\/yp-ab-12427-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}