{"product_id":"yp-ab-05946-100ul","title":"PHC3 Polyclonal Antibody","description":"\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eGene Name:\u003c\/b\u003e PHC3 EDR3 PH3\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eImmunogen:\u003c\/b\u003e Synthesized peptide derived from human protein . at AA range: 720-800\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecificity:\u003c\/b\u003e PHC3 Polyclonal Antibody detects endogenous levels of protein.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eComposition:\u003c\/b\u003e Liquid in PBS containing 50% glycerol,  and 0.02% sodium azide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Polyclonal, Rabbit,IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eDilution ratio:\u003c\/b\u003e WB 1:500-2000 ELISA 1:5000-20000\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurification process:\u003c\/b\u003e The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eConcentration:\u003c\/b\u003e 1 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage:\u003c\/b\u003e -20°C\/1 year\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eBackground:\u003c\/b\u003e function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FCS-type zinc finger.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1\/hPRC-H) at least composed of PCGF2\/RNF110, BMI1\/PCGF4, CBX2\/M33, CBX4\/PC2, CBX8\/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2\/RING2.,\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eFunction:\u003c\/b\u003e function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FCS-type zinc finger.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1\/hPRC-H) at least composed of PCGF2\/RNF110, BMI1\/PCGF4, CBX2\/M33, CBX4\/PC2, CBX8\/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2\/RING2.,\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human;Mouse\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eRange:\u003c\/b\u003e WB;ELISA\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eProtein:\u003c\/b\u003e Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eDA:\u003c\/b\u003e 108kD\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Upingbio","offers":[{"title":"100UL","offer_id":50690091024664,"sku":"YP-Ab-05946-100UL","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/images_b30c1aec-b60f-4bad-a4e2-e7265d6471ad.png?v=1758597872","url":"https:\/\/danabiosci.com\/products\/yp-ab-05946-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}