• Rictor Monoclonal Antibody
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Upingbio

YP-Ab-03420-53UL

Rictor Monoclonal Antibody

Rictor Monoclonal Antibody

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  • Reaction species: Human;Mouse;Monkey
  • Gene Name: RICTOR
  • Protein name: Rapamycin-insensitive companion of mTOR
  • Immunogen: Purified recombinant fragment of human Rictor expressed in E. Coli.
  • Specificity: Rictor Monoclonal Antibody detects endogenous levels of Rictor protein.
  • Composition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
  • Source: Monoclonal, Mouse
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
  • Purification process: Affinity purification
  • Storage: -20°C/1 year
  • Other Names: RICTOR; KIAA1999; Rapamycin-insensitive companion of mTOR; AVO3 homolog; hAVO3
  • Background: RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008],
  • Function: function:Plays an essential role in embryonic growth and development (By similarity). Part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.,similarity:Belongs to the pianissimo family.,subunit:Forms part of the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. TORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to FRAP1 and PROTOR1 within the TORC2 complex. May interact with PROTOR2.,
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