{"product_id":"yp-ab-02366-53ul","title":"TXNRD2 mouse mAb","description":"\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eReaction species:\u003c\/b\u003e Human\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eGene Name:\u003c\/b\u003e txnrd2\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eMolecular weight (DA):\u003c\/b\u003e 56kD\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eImmunogen:\u003c\/b\u003e Purified recombinant human TXNRD2 protein fragments expressed in E.coli.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecificity:\u003c\/b\u003e This antibody detects endogenous levels of TXNRD2 and does not cross-react with related proteins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eComposition:\u003c\/b\u003e Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Monoclonal, Mouse\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eDilution ratio:\u003c\/b\u003e wb 1:1000\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurification process:\u003c\/b\u003e The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eConcentration:\u003c\/b\u003e mg\/ml\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage:\u003c\/b\u003e -20°C\/1 year\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eOther Names:\u003c\/b\u003e mitochondrial;selenoprotein Z;SELZ;Thioredoxin reductase 2;Thioredoxin reductase 2 mitochondrial;thioredoxin reductase 3;thioredoxin reductase beta;Thioredoxin reductase TR3;TR 3;TR;TR beta;TR-beta;TRXR 2;TRXR2;TRXR2_HUMAN;TXNRD 2;Txnrd2.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eBackground:\u003c\/b\u003e thioredoxin reductase 2(TXNRD2) Homo sapiens    This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013],\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eFunction:\u003c\/b\u003e catalytic activity:Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.,cofactor:FAD.,function:Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling.,miscellaneous:The active site is a redox-active disulfide bond. The selenocysteine residue is essential for enzymatic activity.,sequence caution:Translated as Sec.,similarity:Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.,subunit:Homodimer.,tissue specificity:Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614 levels are low.,\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Upingbio","offers":[{"title":"53UL","offer_id":50688650182936,"sku":"YP-Ab-02366-53UL","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/images_eb611f34-f3bd-44d6-95ba-2337487b859c.png?v=1758550268","url":"https:\/\/danabiosci.com\/products\/yp-ab-02366-53ul","provider":"Dana Bioscience","version":"1.0","type":"link"}