{"product_id":"yp-ab-01562-100ul","title":"BAF250b Polyclonal Antibody","description":"\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eGene Name:\u003c\/b\u003e ARID1B\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eImmunogen:\u003c\/b\u003e The antiserum was produced against synthesized peptide derived from human BAF250B. AA range:1371-1420\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecificity:\u003c\/b\u003e BAF250b Polyclonal Antibody detects endogenous levels of BAF250b protein.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eComposition:\u003c\/b\u003e Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Polyclonal, Rabbit,IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eDilution ratio:\u003c\/b\u003e Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurification process:\u003c\/b\u003e The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eConcentration:\u003c\/b\u003e 1 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage:\u003c\/b\u003e -20°C\/1 year\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eOther Names:\u003c\/b\u003e ARID1B; BAF250B; DAN15; KIAA1235; OSA2; AT-rich interactive domain-containing protein 1B; ARID domain-containing protein 1B; BRG1-associated factor 250b; BAF250B; BRG1-binding protein hELD\/OSA1; Osa homolog 2; hOsa2; p250R\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eBackground:\u003c\/b\u003e This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI\/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI\/SNF complex. The associated complexes play opposing roles. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2012],\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eFunction:\u003c\/b\u003e caution:It is uncertain whether Met-1 or Met-59 is the initiator.,function:Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Binds DNA non-specifically.,similarity:Contains 1 ARID domain.,subunit:Component of SWI\/SNF chromatin remodeling complexes, in some of which it can be mutually exclusive with ARID1A\/BAF250A. Component of the BAF (SWI\/SNF-A) complex, which includes at least actin (ACTB), ARID1A, ARID1B\/BAF250, SMARCA2, SMARCA4\/BRG1, ACTL6A\/BAF53, ACTL6B\/BAF53B, SMARCE1\/BAF57, SMARCC1\/BAF155, SMARCC2\/BAF170, SMARCB1\/SNF5\/INI1, and one or more of SMARCD1\/BAF60A, SMARCD2\/BAF60B, or SMARCD3\/BAF60C. In muscle cells, the BAF complex also contains DPF3. Component of the SWI\/SNF-B (PBAF) complex, at least composed of SMARCA4\/BRG1, SMARCB1\/BAF47, ACTL6A\/BAF53A or ACTL6B\/BAF53B, SMARCE1\/BAF57, SMARCD1\/BAF60A,\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human;Rat\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eRange:\u003c\/b\u003e WB;IHC;IF;ELISA\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eProtein:\u003c\/b\u003e AT-rich interactive domain-containing protein 1B\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eDA:\u003c\/b\u003e 170kD\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Upingbio","offers":[{"title":"100UL","offer_id":50689876721944,"sku":"YP-Ab-01562-100UL","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/images_656d3524-933c-4e1f-a2d9-eb694b41aab3.png?v=1758591982","url":"https:\/\/danabiosci.com\/products\/yp-ab-01562-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}