{"product_id":"yp-ab-00859-100ul","title":"PCAF (Acetyl Lys428) Polyclonal Antibody","description":"\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eGene Name:\u003c\/b\u003e KAT2B\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eImmunogen:\u003c\/b\u003e Synthesized acetyl-peptide derived from the human PCAF around the acetylation site of K428.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecificity:\u003c\/b\u003e Acetyl-PCAF (K428) Polyclonal AntibodySynthesized peptide derived from the human PCAF around the acetylation site of K428.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eComposition:\u003c\/b\u003e Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Polyclonal, Rabbit,IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eDilution ratio:\u003c\/b\u003e WB 1:500-2000;IHC-p 1:50-300\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurification process:\u003c\/b\u003e The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eConcentration:\u003c\/b\u003e 1 mg\/ml\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage:\u003c\/b\u003e -20°C\/1 year\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eOther Names:\u003c\/b\u003e KAT2B; PCAF; Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; Histone acetylase PCAF; Lysine acetyltransferase 2B; P300\/CBP-associated factor; P\/CAF\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eBackground:\u003c\/b\u003e CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and\/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300\/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300\/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008],\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eFunction:\u003c\/b\u003e chromatin organization, chromatin remodeling, transcription, regulation of transcription, DNA-dependent, protein amino acid acetylation, N-terminal protein amino acid acetylation, cell cycle, cell cycle arrest, negative regulation of cell proliferation, response to endogenous stimulus, response to hormone stimulus, response to organic substance,chromatin modification, covalent chromatin modification, histone modification, histone acetylation, N-terminal peptidyl-lysine acetylation, peptidyl-lysine modification, peptidyl-lysine acetylation, cell cycle process, N-terminal protein amino acid modification, response to insulin stimulus, cellular response to insulin stimulus, cellular response to hormone stimulus, regulation of cell proliferation, response to peptide hormone stimulus, protein amino acid acylation,regulation of transcription, regulation of RNA metabolic process, chromosome orga\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human;Mouse\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eRange:\u003c\/b\u003e WB;IHC\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eProtein:\u003c\/b\u003e Histone acetyltransferase KAT2B\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eDA:\u003c\/b\u003e 93kD\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Upingbio","offers":[{"title":"100UL","offer_id":50689836548376,"sku":"YP-Ab-00859-100UL","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/images_b5a9cd9a-df35-46ac-a159-c22c21802b14.png?v=1758591218","url":"https:\/\/danabiosci.com\/products\/yp-ab-00859-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}