{"product_id":"v9446-20ug","title":"Recombinant Cdc20 Antibody","description":"\u003cp\u003eRequired for full ubiquitin ligase activity of the anaphase promoting complex\/cyclosome (APC\/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC\/C ternary complex is inactive and in anaphase the CDC20-APC\/C binary complex is active in degrading substrates. The CDC20-APC\/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC\/C-induced degradation of NEUROD2 induces presynaptic differentiation. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Rabbit","offer_id":49429504688408,"sku":"V9446-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_53f3aa8d-0739-4461-b5b1-bab64895b4e7.jpg?v=1733302457","url":"https:\/\/danabiosci.com\/products\/v9446-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}