{"product_id":"v9232-100ug","title":"Th-Pok Antibody \/ ZBTB7B","description":"\u003cp\u003eTH-POK (T-helper-inducing POZ\/Kr ppel-like factor), also known as zinc finger protein 67 (ZFP67), zinc finger and BTB domain-containing protein 7B or Kr ppel-related zinc finger protein cKrox, is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus, TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically, the presence of TH-POK directs positively selected thymocytes to the CD4 lineage, whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes, such as COL1A1, COL1A2 and Fibronectin.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":49429596602648,"sku":"V9232-100UG","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_48df80ef-c05f-4021-b2c8-c7a72772299a.jpg?v=1733304186","url":"https:\/\/danabiosci.com\/products\/v9232-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}