{"product_id":"v9224-100ug","title":"ZBTB46 Antibody \/ BTBD4 \/ ZNF340","description":"\u003cp\u003eBTBD4 (BTB\/POZ domain-containing protein 4), also known as zinc finger protein 340 (ZNF340) or zinc finger and BTB domain-containing protein 46 (ZBTB46), is a 589 amino acid protein that contains one BTB\/POZ domain. The BTB\/POZ domain mediates homomeric and heteromeric POZ-POZ inter- actions and is common to transcriptional regulators involved in chromatin modeling. In several BTB\/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT\/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this tran- scriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":49429601812760,"sku":"V9224-100UG","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_07463bf5-a144-4219-a703-13a80f57e162.jpg?v=1733304252","url":"https:\/\/danabiosci.com\/products\/v9224-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}