{"product_id":"v9194-20ug","title":"ICAM1 Antibody \/ CD54","description":"\u003cp\u003eRecognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a\/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b\/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Mouse","offer_id":49429635203352,"sku":"V9194-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_4c793323-f707-416a-9f10-8e615ecaeaad.jpg?v=1733304483","url":"https:\/\/danabiosci.com\/products\/v9194-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}