{"product_id":"v8442-20ug","title":"AKT1 Antibody","description":"\u003cp\u003eRecognizes a protein of 62kDa, which is identified as AKT1. The serine\/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin\/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Rabbit","offer_id":49429974188312,"sku":"V8442-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_a360adc1-690e-4d44-a837-048c48402494.jpg?v=1733309997","url":"https:\/\/danabiosci.com\/products\/v8442-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}