{"product_id":"v8355-20ug","title":"Aurora B Antibody \/ AURKB","description":"\u003cp\u003eRecognizes a protein of 39kDa, which is identified as Aurora B. The serine\/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Mouse","offer_id":49430005580056,"sku":"V8355-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_cdf0cf7f-fbef-4443-a62f-b98c5b59e315.jpg?v=1733310518","url":"https:\/\/danabiosci.com\/products\/v8355-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}