{"product_id":"v8352-20ug","title":"CD4 Antibody","description":"\u003cp\u003eCD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Rat","offer_id":49430006497560,"sku":"V8352-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/danabiosci.com\/products\/v8352-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}