{"product_id":"v8214-100ug","title":"Aurora B Antibody \/ AURKB","description":"\u003cp\u003eRecognizes a protein of 39kDa, which is identified as Aurora B. The serine\/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":49430074917144,"sku":"V8214-100UG","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_a0623fab-429d-4f52-a66b-359d1df11c1b.jpg?v=1733311411","url":"https:\/\/danabiosci.com\/products\/v8214-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}