{"product_id":"v7966-100ug","title":"MTF1 Antibody \/ Metal regulatory transcription factor 1","description":"\u003cp\u003eThe metal-responsive element (MRE)-binding transcription factor (MTF-1) stimulates the expression of metallothioneins in response to the exposure of cells to heavy metals. MTF-1 contains six zinc fingers in the DNA binding domain. The phosphorylation of MTF-1 in response to metal exposure appears to play a significant role in the ability of MTF-1 to activate metallothionein transcription. In addition to its role in metallothionein activation, MTF-1 is involved in a post-transcription regulatory complex for ribosomal protein S25. MTF-1, La and p53 inhibit the nuclear export of S25 mRNA in response to nutrient depravation. Furthermore, MTF-1 acts as a chromatin insulator on integrated transgenes in cultured cells to insulate active loci against chromatin silencing.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":49430182756632,"sku":"V7966-100UG","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_98eae559-f4b7-4a64-bc7e-f203082120ed.jpg?v=1733313077","url":"https:\/\/danabiosci.com\/products\/v7966-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}