{"product_id":"v7447-20ug","title":"SPTBN2 Antibody \/ Spectrin beta III","description":"\u003cp\u003eSpectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [RefSeq]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Rabbit","offer_id":49431255154968,"sku":"V7447-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_073b8505-5326-432d-8790-4b85fba27e1a.jpg?v=1733341923","url":"https:\/\/danabiosci.com\/products\/v7447-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}