{"product_id":"v7147-20ug","title":"PMEL17 \/ Melanoma gp100 Antibody","description":"PMEL17\/Melanoma gp100\/SILV plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. [UniProt]\u003cp\u003eThe gp100 molecule is a 100kDa glycosylated protein that is cleaved into a small (26kDa) carboxy-terminal fragment and a larger amino- terminal section (60-64 kDa), which is subsequently cleaved to generate 26kDa and 34-38kDa fragments.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Mouse","offer_id":49431349788952,"sku":"V7147-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_b33ad709-21eb-4f1e-919f-8319aed4eccf.jpg?v=1733344565","url":"https:\/\/danabiosci.com\/products\/v7147-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}