{"product_id":"v5178-20ug","title":"HLA-ABC Antibody (MHC I)","description":"\u003cp\u003eReacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Immunoprecipitation of lactoperoxidase radioiodinated cell surface proteins and surface sialoglycoproteins radiolabeled by sodium metaperiodate\/tritiated sodium borohydride technique confirmed the structure gp44,p12 (consisting of a 44kDa glycopeptide linked with a non-glycosylated 12kDa peptide) typical for MHC class I antigen(s) as a structure recognized by Bra23\/9. Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Mouse","offer_id":49431592042776,"sku":"V5178-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/danabiosci.com\/products\/v5178-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}