{"product_id":"v4497-100ug","title":"Topoisomerase II alpha Antibody \/ TOP2A","description":"\u003cp\u003eThe topoisomerase II-Alpha isoform is a 170kDa nuclear protein and plays an important role in DNA synthesis and RNA transcription, as well as chromosomal segregation during mitosis. Topoisomerase II-Alpha is reported to be a sensitive and specific marker of late S-, G2- \u0026amp; M-phases in transformed and developmentally regulated normal cells, and has been shown to be over-expressed in many human cancers. Decreased expression of Topoisomerase II-Alpha is the predominant mechanism of resistance to several chemotherapeutic agents.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49473989083416,"sku":"V4497-100UG","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_c842ed39-e781-46c8-939d-deeb3b5fdff3.jpg?v=1734422816","url":"https:\/\/danabiosci.com\/products\/v4497-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}