{"product_id":"v4353-20ug","title":"SNW1 Antibody \/ NCoA-62 \/ SKIP","description":"\u003cp\u003eNuclear receptor coactivator NCOA62\/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Mouse","offer_id":49474092531992,"sku":"V4353-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_7b131c6d-a13e-4770-83d4-71f75dd7c413.jpg?v=1734424204","url":"https:\/\/danabiosci.com\/products\/v4353-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}