{"product_id":"v4336-100ug","title":"C\/EBP epsilon Antibody \/ CEBPE","description":"\u003cp\u003eThe transcription factor C\/EBP Alpha (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C\/EBP Alpha regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C\/EBP Alpha uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic Alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C\/EBP Alpha appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C\/EBP beta, C\/EBP gamma, C\/EBP delta and C\/EBP epsilon, all of which exhibit similar DNA-binding specificities and affinities to C\/EBP Alpha. Furthermore, C\/EBP beta and C\/EBP delta readily form heterodimers both with each other as well as with C\/EBP Alpha.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":49474102460696,"sku":"V4336-100UG","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_afff4f37-82d5-4c1e-8596-e170f3a32cce.jpg?v=1734424379","url":"https:\/\/danabiosci.com\/products\/v4336-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}