{"product_id":"v4236-100ug","title":"GPRC5A Antibody \/ Retinoic acid-induced protein 3 \/ PEIG-1","description":"\u003cp\u003eRetinoic acid-induced protein 3 (RAI3), also called Phorbol ester induced gene 1 (PEIG-1) and GPRC5A, is an transmembrane G protein-coupled receptor that affects many essential biological processes including embryogenesis, cell growth, differentiation, and apoptosis. PEIG-1 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate PEIG-1 during its transcription in embryonal carcinoma differentiation. PEIG-1 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of PEIG-1 and represses its expression at the beginning of apoptosis. PEIG-1 is a potential molecular target for diagnosing breast cancer, and selective suppression of signals from PEIG-1 may have a place in breast cancer treatments.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":49474179957016,"sku":"V4236-100UG","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_49ec5293-0e24-4a21-a8de-651919531cc1.jpg?v=1734425375","url":"https:\/\/danabiosci.com\/products\/v4236-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}