{"product_id":"v3849-20ug","title":"CD25 Antibody \/ IL2RA","description":"\u003cp\u003eRecognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes\/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias\/lymphomas and inflammatory\/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R b-chain, p75) and CD132 (common g-chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This mAb recognizes the epitope B, which is located at residue 3-104 of CD25 and does not block IL-2 binding to CD25.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Mouse","offer_id":49474383446296,"sku":"V3849-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_cd6c2be4-898b-457e-988d-a77f0e65406f.jpg?v=1734428963","url":"https:\/\/danabiosci.com\/products\/v3849-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}