{"product_id":"v3658ihc-7ml","title":"Tyrosinase Antibody","description":"\u003cp\u003eThis mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1\/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"7 ml \/ Mouse","offer_id":49474442723608,"sku":"V3658IHC-7ML","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_5847b97c-85a1-4d3a-9b1e-3f88fd084f9c.jpg?v=1734430984","url":"https:\/\/danabiosci.com\/products\/v3658ihc-7ml","provider":"Dana Bioscience","version":"1.0","type":"link"}