{"product_id":"v3548-20ug","title":"CD8A Antibody","description":"\u003cp\u003eCD8 is a cell surface receptor expressed either as a heterodimer with the beta chain or as a homodimer. A majority of thymocytes and a subpopulation of mature Tcells and NK cells express CD8a. It binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in Tcell development and activation of mature Tcells. For mature Tcells, CD8 and 4 are mutually exclusive, so antibody to CD8 is generally used in conjunction with antibody to CD4. CD8a antibody is a useful marker for distinguishing helper\/inducer T-lymphocytes, and most peripheral Tcell lymphomas are CD4+\/CD8-. Anaplastic large cell lymphoma is usually CD4+\/CD8-, and in T-lymphoblastic lymphoma\/leukemia, they are often co-expressed. It is also found in littoral cell angioma of the spleen.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug \/ Mouse","offer_id":49474480898328,"sku":"V3548-20UG","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_59b6c038-c304-4822-bec2-608ee6336552.jpg?v=1734432335","url":"https:\/\/danabiosci.com\/products\/v3548-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}