{"product_id":"v2584saf-100ug","title":"HLA-DR Antibody (MHC II)","description":"\u003cp\u003eThis antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes\/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3\/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":49474704343320,"sku":"V2584SAF-100UG","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_323025c1-a677-4cb0-bd57-b75f61f64c86.jpg?v=1734441205","url":"https:\/\/danabiosci.com\/products\/v2584saf-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}