{"product_id":"tnfrsf1a-antibody-abccs64885","title":"TNFRSF1A Antibody","description":"\u003ch4\u003eSize\u003c\/h4\u003e\u003cp\u003e100ul\u003c\/p\u003e\u003ch4\u003eClone Number\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eAliases\u003c\/h4\u003e\u003cp\u003eCD120a antibody; FPF antibody; MGC19588 antibody; p55 antibody; p55-R antibody; p60 antibody; TBP1 antibody; TBPI antibody; TNF R antibody; TNF R55 antibody; TNF-R1 antibody; TNF-RI antibody; TNFAR antibody; TNFR-I antibody; TNFR1 antibody; TNFR55 antibody; TNFR60 antibody; TNFRI antibody; TNFRSF1a antibody; TNR1A_HUMAN antibody; Tumor necrosis factor receptor 1 antibody; Tumor necrosis factor receptor superfamily, member 1A antibody; Tumor necrosis factor receptor type 1 antibody; Tumor necrosis factor receptor type I antibody; Tumor necrosis factor-binding protein 1 antibody\u003c\/p\u003e\u003ch4\u003eImmunogen Species\u003c\/h4\u003e\u003cp\u003eHomo sapiens (Human)\u003c\/p\u003e\u003ch4\u003eUniProt ID\u003c\/h4\u003e\u003cp\u003eP19438\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eRecombinant Human Tumor necrosis factor receptor superfamily member 1A protein (249-455AA)\u003c\/p\u003e\u003ch4\u003eRaised in\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eSpecies Reactivity\u003c\/h4\u003e\u003cp\u003eHuman\u003c\/p\u003e\u003ch4\u003eTested Applications\u003c\/h4\u003e\u003cp\u003eELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eReceptor for TNFSF2\/TNF-alpha and homotrimeric TNFSF1\/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003ePurification Method\u003c\/h4\u003e\u003cp\u003e\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003ch4\u003eConjugate\u003c\/h4\u003e\u003cp\u003eNon-conjugated\u003c\/p\u003e\u003ch4\u003eBuffer\u003c\/h4\u003e\u003cp\u003ePreservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eLiquid\u003c\/p\u003e\u003ch4\u003eStroage\u003c\/h4\u003e\u003cp\u003eUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003ch4\u003eTarget Names\u003c\/h4\u003e\u003cp\u003eTNFRSF1A\u003c\/p\u003e\u003ch4\u003eResearch Areas\u003c\/h4\u003e\u003cp\u003eCancer; Cardiovascular; Cell biology; Immunology; Signal transduction; Stem cells\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"Default Title","offer_id":42255189672170,"sku":"ABCCS64885","price":299.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_d8f2f39f-3a71-4d21-ba01-ff36afa32b06.png?v=1650625210","url":"https:\/\/danabiosci.com\/products\/tnfrsf1a-antibody-abccs64885","provider":"Dana Bioscience","version":"1.0","type":"link"}