{"product_id":"terf1-antibody-abccs53152","title":"TERF1 Antibody","description":"\u003ch4\u003eSize\u003c\/h4\u003e\u003cp\u003e100ug\u003c\/p\u003e\u003ch4\u003eClone Number\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eAliases\u003c\/h4\u003e\u003cp\u003ehTRF1 AS antibody; NIMA interacting protein 2 antibody; NIMA-interacting protein 2 antibody; PIN 2 antibody; PIN2 antibody; t TRF1 antibody; Telomeric protein Pin2 antibody; Telomeric protein Pin2\/TRF1 antibody; Telomeric repeat binding factor (NIMA interacting) 1 antibody; Telomeric repeat binding factor 1 antibody; Telomeric repeat binding protein 1 antibody; Telomeric repeat-binding factor 1 antibody; TERF 1 antibody; Terf1 antibody; TERF1_HUMAN antibody; TRBF 1 antibody; TRBF1 antibody; TRF 1 antibody; TRF antibody; TTAGGG repeat binding factor 1 antibody; TTAGGG repeat-binding factor 1 antibody\u003c\/p\u003e\u003ch4\u003eImmunogen Species\u003c\/h4\u003e\u003cp\u003eHomo sapiens (Human)\u003c\/p\u003e\u003ch4\u003eUniProt ID\u003c\/h4\u003e\u003cp\u003eP54274\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eRecombinant Human Telomeric repeat-binding factor 1 protein (260-439AA)\u003c\/p\u003e\u003ch4\u003eRaised in\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eSpecies Reactivity\u003c\/h4\u003e\u003cp\u003eHuman\u003c\/p\u003e\u003ch4\u003eTested Applications\u003c\/h4\u003e\u003cp\u003eELISA, IHC; Recommended dilution: IHC:1:20-1:200\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eBinds the telomeric double-stranded 5\\'-TTAGGG-3\\' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5\\'-TTAGGG-3\\' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003ePurification Method\u003c\/h4\u003e\u003cp\u003e\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003ch4\u003eConjugate\u003c\/h4\u003e\u003cp\u003eNon-conjugated\u003c\/p\u003e\u003ch4\u003eBuffer\u003c\/h4\u003e\u003cp\u003ePreservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eLiquid\u003c\/p\u003e\u003ch4\u003eStroage\u003c\/h4\u003e\u003cp\u003eUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003ch4\u003eTarget Names\u003c\/h4\u003e\u003cp\u003eTERF1\u003c\/p\u003e\u003ch4\u003eResearch Areas\u003c\/h4\u003e\u003cp\u003eEpigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"Default Title","offer_id":42297538805994,"sku":"ABCCS53152","price":299.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_49441b4e-0667-423e-b2a2-fe503ba4d282.png?v=1650705730","url":"https:\/\/danabiosci.com\/products\/terf1-antibody-abccs53152","provider":"Dana Bioscience","version":"1.0","type":"link"}