{"product_id":"rq8230","title":"NECAB3 Antibody \/ N-terminal EF-hand calcium-binding protein 3","description":"\u003cp\u003eN-terminal EF-hand calcium-binding protein 3 is a protein that in humans is encoded by the NECAB3 gene. The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49475334013208,"sku":"RQ8230","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_caf966a4-815e-4c68-82ba-72b42c57a17e.jpg?v=1734446769","url":"https:\/\/danabiosci.com\/products\/rq8230","provider":"Dana Bioscience","version":"1.0","type":"link"}