{"product_id":"rq7665","title":"BAF57 Antibody \/ BRG1-associated factor 57 \/ SMARCE1","description":"\u003cp\u003eSWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (SMARCE1), also called BRG1-associated factor 57 (BAF57), is a protein that in humans is encoded by the SMARCE1 gene. The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI\/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI\/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI\/SNF complex. Unlike most of the SWI\/SNF complex proteins, this protein has no yeast counterpart.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49475409412376,"sku":"RQ7665","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_120c9d03-b47f-4ca3-abb1-9f77e7a35abd.jpg?v=1734448683","url":"https:\/\/danabiosci.com\/products\/rq7665","provider":"Dana Bioscience","version":"1.0","type":"link"}