{"product_id":"rq7616","title":"RNase H2 subunit A Antibody \/ RNASEH2A","description":"\u003cp\u003eRibonuclease H2 subunit A, also known as RNase H2 subunit A, is an enzyme that in humans is encoded by the RNASEH2A gene. The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49475411869976,"sku":"RQ7616","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_e969204b-202a-4a2b-9daf-8d4108a056a5.jpg?v=1734448861","url":"https:\/\/danabiosci.com\/products\/rq7616","provider":"Dana Bioscience","version":"1.0","type":"link"}