{"product_id":"rq7273","title":"Ark-1 Antibody \/ Aurora-related kinase 1 \/ Aurka","description":"\u003cp\u003eAURKA (Aurora kinase A), also called ARK-1 (Aurora-related kinase 1), AurA, AIK, AURORA2, BTAK, PPP1R47, STK7, STK15, and STK6 is a mitotic centrosomal protein kinase. The main role of AURKA\/ARK-1 in tumor development is in controlling chromosome segregation during mitosis. Aurora A \/ Aurora-related kinase 1 is a member of a family of mitotic serine\/threonine kinases. The AURKA gene is overexpressed in many human cancers. Ectopic overexpression in mammalian cells induces centrosome amplification, chromosome instability, and oncogenic transformation, a phenotype characteristic of loss-of-function mutations of p53.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49475433890072,"sku":"RQ7273","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_3024d13f-0bc1-42c1-8e48-2b580a231924.jpg?v=1734450035","url":"https:\/\/danabiosci.com\/products\/rq7273","provider":"Dana Bioscience","version":"1.0","type":"link"}