{"product_id":"rq7083","title":"Integrin alpha E Antibody \/ Cd103","description":"\u003cp\u003eITGAE (INTEGRIN, ALPHA-E), also known as CD103, is an integrin protein that in human is encoded by the ITGAE gene. The ITGAE gene is mapped to chromosome 17p13 by inclusion within a BAC contig. ITGAE is expressed widely on intraepithelial lymphocyte (IEL) T cells (both alpha-beta T cells and gamma-delta T cells) and on some peripheral regulatory T cells(Tregs) which is important for decreasing the immune response and appears to play a crucial role in the prevention of autoimmune diseases. ITGAE shares overall homology with other alpha integrins but has a unique 55-amino acid extra region located just N-terminal to the I domain that contains 18 consecutive charged residues and a proteolytic cleavage site.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49475444769048,"sku":"RQ7083","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_a5cf8723-f3c6-4594-bb00-c64e35825de3.jpg?v=1734450699","url":"https:\/\/danabiosci.com\/products\/rq7083","provider":"Dana Bioscience","version":"1.0","type":"link"}