{"product_id":"rq6516","title":"SLFN11 Antibody \/ Schlafen family member 11","description":"\u003cp\u003eSchlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene. SLFN11 is a nuclear protein that belongs to the Schlafen (SLFN) family of genes involved in cell cycle regulation and growth inhibition. Expression of SLFN11 predicts sensitivity of cancer cell lines to DNA-damaging agents. Evidence suggests that in the presence of DNA-targeted therapies, SLFN11 is recruited to stressed replication forks where it blocks replication leading to cell death. SLFN11 is being explored as a predictive biomarker for response to DNA-targeted therapies.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49475852304664,"sku":"RQ6516","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_29bc66b9-257f-4f08-a7cb-7f2980987e47.jpg?v=1734461339","url":"https:\/\/danabiosci.com\/products\/rq6516","provider":"Dana Bioscience","version":"1.0","type":"link"}