{"product_id":"rq6463","title":"Claudin 2 Antibody \/ CLDN2","description":"\u003cp\u003eClaudin-2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49475856138520,"sku":"RQ6463","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_26ce596b-8070-4015-8f15-1e5897864dc5.jpg?v=1734461523","url":"https:\/\/danabiosci.com\/products\/rq6463","provider":"Dana Bioscience","version":"1.0","type":"link"}