{"product_id":"rq6121","title":"Apc5 Antibody \/ Anaphase-promoting complex subunit 5","description":"\u003cp\u003eAnaphase-promoting complex subunit 5 is an enzyme that in humans is encoded by the ANAPC5 gene. This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex\/cyclosome (APC\/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC\/C and for the interaction of APC\/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49475885400344,"sku":"RQ6121","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_9d1ec49f-1ba8-4969-9620-10e0f15f26f3.jpg?v=1734462656","url":"https:\/\/danabiosci.com\/products\/rq6121","provider":"Dana Bioscience","version":"1.0","type":"link"}