{"product_id":"rq5899","title":"Nectin 1 Antibody \/ PVRL1","description":"\u003cp\u003eThe NECTIN1 gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate\/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL\/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49475909615896,"sku":"RQ5899","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_9e6e18f2-0e3a-4468-abbf-d425aac81867.jpg?v=1734463449","url":"https:\/\/danabiosci.com\/products\/rq5899","provider":"Dana Bioscience","version":"1.0","type":"link"}