{"product_id":"rq5512","title":"PLK1 Antibody","description":"\u003cp\u003eSerine\/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine\/threonine-protein kinase 13 (STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase1) gene. Plk1 is an early trigger for G2\/M transition. It supports the functional maturation of the centrosome in late G2\/early prophase and establishment of the bipolar spindle. Also, Plk1 phosphorylates and activates cdc25C, a phosphatase that dephosphorylates and activates the cyclinB\/cdc2 complex. Studies have shown that the loss of PLK1 expression can induce pro-apoptotic pathways and inhibit growth. Based on yeast and murine studies of meiosis, human PLK1 may also have a regulatory function in meiosis.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Mouse","offer_id":49475967582488,"sku":"RQ5512","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_2db36b8e-ba26-4d94-a7ae-3c745d6d54b4.jpg?v=1734464739","url":"https:\/\/danabiosci.com\/products\/rq5512","provider":"Dana Bioscience","version":"1.0","type":"link"}