{"product_id":"rq5205","title":"P Glycoprotein Antibody \/ MDR1 \/ ABCB1","description":"\u003cp\u003eThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR\/TAP subfamily. Members of the MDR\/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [RefSeq]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul \/ Rabbit","offer_id":49475989078296,"sku":"RQ5205","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_fdc1456f-ea48-4970-9258-b2c109d39737.jpg?v=1734465505","url":"https:\/\/danabiosci.com\/products\/rq5205","provider":"Dana Bioscience","version":"1.0","type":"link"}