{"product_id":"rq4482","title":"NOX4 Antibody \/ NADPH oxidase 4","description":"\u003cp\u003eConstitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA\/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3\/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul \/ Rabbit","offer_id":49476118642968,"sku":"RQ4482","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_2403e8d9-19cc-4a62-b6a5-c763fd08a868.jpg?v=1734467626","url":"https:\/\/danabiosci.com\/products\/rq4482","provider":"Dana Bioscience","version":"1.0","type":"link"}