{"product_id":"rq4383","title":"GITR Antibody \/ TNFRSF18","description":"\u003cp\u003eTumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR, is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476132700440,"sku":"RQ4383","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_d7ca2559-450c-4ec8-805d-af8d68af9be2.jpg?v=1734467926","url":"https:\/\/danabiosci.com\/products\/rq4383","provider":"Dana Bioscience","version":"1.0","type":"link"}