{"product_id":"rcc2-polyclonal-antibody-abcb04804","title":"RCC2 Polyclonal Antibody","description":"\u003ch4\u003eAb type\u003c\/h4\u003e\u003cp\u003ePrimary antibody\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eRCC2\/TD-60 is a member of the RCC1 (regulator of chromosome condensation 1) family of guanine nucleotide exchange factors. RCC2\/TD-60 is associated with the chromosome passenger complex (CPC), which also consists of aurora B kinase, borealin, INCENP (inner centromere protein) and survivin. The CPC acts at various stages of mitosis, interacts with microtubules and is required for proper chromosome segregation and cytokinesis. Regulation of aurora B kinase is key in the regulation of the CPC. In late mitosis, RCC2\/TD-60 is required for spindle assembly and recruitment of survivin and aurora B. RCC2\/TD-60 is also required for aurora B activation in vitro and localization of the CPC to centromeres.\u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman;Mouse\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eThe antiserum was produced against synthesized peptide derived from human RCC2. AA range:473-522\u003c\/p\u003e\u003ch4\u003eStorage Stability\u003c\/h4\u003e\u003cp\u003e-20°C for one year\u003c\/p\u003e\u003ch4\u003eConcentration\u003c\/h4\u003e\u003cp\u003e1 mg\/ml\u003c\/p\u003e\u003ch4\u003eMolecularWeight_Da\u003c\/h4\u003e\u003cp\u003e56085\u003c\/p\u003e\u003ch4\u003esynonyms\u003c\/h4\u003e\u003cp\u003eRCC2; KIAA1470; TD60; Protein RCC2; RCC1-like protein TD-60; Telophase disk protein of 60 kDa\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42404355604714,"sku":"ABCB04804","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_e8cb08e4-d6a6-48a2-a401-7c2abd0f83c4.png?v=1645219021","url":"https:\/\/danabiosci.com\/products\/rcc2-polyclonal-antibody-abcb04804","provider":"Dana Bioscience","version":"1.0","type":"link"}